The unimposing problem

Poor handling of inhalation devices leads to insufficient drug dose in the lungs.

Patients with chronic lung disease suffer from a major problem: the treatment success of their pneumological disease depends to a large extent on the correct handling of their inhalers, because the drug must reach the lungs to be effective. But the inhaler market is very opaque, with too many different models. From the patient’s point of view, the handling of the different devices sometimes differs significantly. In Germany alone, over 160 different combination preparations with MDI inhalers (metered dose inhalers and sprays) and DPI inhalers (dry powder inhalers) are approved. The resulting application errors are expensive and fatal. The consequences are serious: patients who are underdosed have more severe disease progressions.

90%

90% of patients make application errors[1], [2], [3]

50%

50% of these are so-called critical errors, i.e. they have a negative effect on the dose that still reaches the lungs[1], [2], [3]

Poor patient inhalation technique correlates with poor disease progression and severe exacerbations[4], [5]

[1] Respiratory Medicine (2008) 102, 593–604

[2] Respiratory Medicine (2011) 105, 930e938

[3] Respiratory Medicine (2013) 107, 37e46

[4] Price et. al. Inhaler errors in the CRITIKAL study

[5] Molimard et. al. Eur Respir J 2017; 49: 1601794

[6] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693508

[7] https://www.who.int/news-room/q-a-detail/asthma

[8] https://www.who.int/en/news-room/fact-sheets/detail/chronic-obstructive-pulmonary-disease-(copd)

[9] https://www.who.int/news-room/fact-sheets/detail/asthma

More than 600 million people worldwide suffer from chronic respiratory tract infections and more than 3.5 million patients die from their consequences every year. [6], [7], [8], [9]

However, studies impressively prove that improved handling of the inhalation systems enables a significantly better therapy success. This is where the Gesundheits-App Kata® can offer real added value for patients, relatives and treating physicians.

This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 867249.

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